Neomycin Sulfate,CAS:1405-10-3,H.S code:292249

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CAS:1405-10-3,

Neomycin sulfate is an antibiotic used to treat various bacterial infections. It is effective against a range of Gram-negative and some Gram-positive bacteria. Commonly used in topical formulations, such as creams and ointments, it helps prevent infections in minor cuts, burns, and skin conditions. Additionally, it can be administered orally to reduce bowel bacteria before surgical procedures or to treat hepatic coma. Due to its potential for toxicity, especially when used systemically, it is typically reserved for specific cases under medical supervision.

CAS: 1405-10-3

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Neomycin sulfate is an antibiotic that belongs to the aminoglycoside class. It is primarily used to treat infections caused by certain bacteria. Here are some common uses and important information about neomycin sulfate:

### Uses
1. **Topical Infections**:
- Often used in topical formulations (creams, ointments) to treat skin infections, especially those caused by Gram-negative bacteria.

2. **Eye Infections**:
- Found in some ophthalmic solutions to treat bacterial eye infections.

3. **Ear Infections**:
- Used in ear drops to treat external ear infections (otitis externa).

4. **Bowel Preparation**:
- Administered orally to reduce intestinal bacteria before surgical procedures, especially bowel surgeries.

5. **Systemic Infections**:
- In some cases, it may be used for serious systemic infections caused by susceptible organisms, though this is less common due to potential toxicity.

### Mechanism of Action
- Neomycin works by binding to bacterial ribosomes, inhibiting protein synthesis, which ultimately leads to bacterial cell death.

### Side Effects
- Common side effects can include:
- Skin irritation (for topical use)
- Nausea, vomiting, or diarrhea (for oral use)
- Hearing loss or kidney toxicity, especially with systemic use or prolonged exposure

### Precautions
- Use with caution in patients with renal impairment, as neomycin can be nephrotoxic.
- Not recommended for use in pregnant or breastfeeding women unless deemed essential by a healthcare provider.

### Conclusion
Neomycin sulfate is a versatile antibiotic used mainly for localized infections and as part of bowel preparation. However, due to its potential for toxicity, especially with systemic use, it should be used under medical supervision.

More Information
SKU	1405-10-3
EINECS	215-773-1
HS Code	292249
Formula	C23h48n6o17s
Application	Pharma & Personal Care
Usage	Neomycin sulfate is an antibiotic used to treat various bacterial infections. It is effective against a range of Gram-negative and some Gram-positive bacteria. Commonly used in topical formulations, such as creams and ointments, it helps prevent infections in minor cuts, burns, and skin conditions. Additionally, it can be administered orally to reduce bowel bacteria before surgical procedures or to treat hepatic coma. Due to its potential for toxicity, especially when used systemically, it is typically reserved for specific cases under medical supervision.