Terbinafine Hydrochloride,CAS:78628-80-5,used in Pharma & Personal Care

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CAS:78628-80-5,

Terbinafine HCL is an antifungal medication commonly used to treat fungal infections of the skin and nails, such as athlete's foot, ringworm, and nail fungus. It works by inhibiting the growth of fungi, leading to their death. The medication is typically taken orally in tablet form or applied topically as a cream or solution. Treatment duration varies based on the infection type and severity, often lasting several weeks. It's essential to follow a healthcare provider's instructions and complete the full course to ensure effective treatment and prevent recurrence.

CAS: 78628-80-5

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Terbinafine hydrochloride (HCL) is an antifungal medication commonly used to treat various fungal infections. Here are some key points about its usage:

### Indications
1. **Dermatophyte Infections**:
- Effective against infections like athlete's foot (tinea pedis), ringworm (tinea corporis), and jock itch (tinea cruris).

2. **Onychomycosis**:
- Used for the treatment of fungal nail infections, particularly those caused by dermatophytes.

3. **Candida Infections**:
- Sometimes prescribed for specific types of candidiasis, although other antifungals are more commonly used for these infections.

### Administration
- **Forms**: Available in oral tablets and topical formulations (cream, gel).
- **Dosage**: Dosage varies based on the type and severity of the infection:
- **Oral**: Typically, 250 mg once daily for most infections. Duration can range from a few weeks to several months for nail infections.
- **Topical**: Applied once or twice daily as directed by a healthcare professional.

### Mechanism of Action
- Terbinafine works by inhibiting an enzyme called squalene epoxidase, which is crucial for the synthesis of ergosterol, a key component of fungal cell membranes. This leads to cell death and the elimination of the infection.

### Side Effects
- Common side effects may include gastrointestinal symptoms (nausea, diarrhea), headache, skin rash, and liver enzyme alterations.
- Rare but serious side effects can include liver damage and severe allergic reactions.

### Precautions
- **Liver Function**: Liver function tests may be necessary before starting treatment, especially for patients with a history of liver disease.
- **Drug Interactions**: Terbinafine may interact with other medications, so it's essential to inform your healthcare provider about all medicines you are taking.

### Conclusion
Terbinafine HCL is a widely used and effective treatment for various fungal infections, particularly those affecting the skin and nails. As with any medication, it should be used under the guidance of a healthcare professional to ensure safety and efficacy.

More Information
SKU	78628-80-5
EINECS	616-640-4
HS Code	293499
Formula	C21h26cln
Application	Pharma & Personal Care
Usage	Terbinafine HCL is an antifungal medication commonly used to treat fungal infections of the skin and nails, such as athlete's foot, ringworm, and nail fungus. It works by inhibiting the growth of fungi, leading to their death. The medication is typically taken orally in tablet form or applied topically as a cream or solution. Treatment duration varies based on the infection type and severity, often lasting several weeks. It's essential to follow a healthcare provider's instructions and complete the full course to ensure effective treatment and prevent recurrence.